【Clinical manifestations】
Approximately 90% of Legionellosis↔≥ ÷ is caused by Legionella pneu♠♣mophila. The causative agent of Legi"£•♥onella pneumonia is Legionella pneumophila, wh∏<>ich accounts for 2 to →∑↑☆5% of community-acquired pneumonia . The±π symptoms of Legionella disease vary wi®≤÷≠dely, from common cold and ×♣"low fever to high fever, with changes inσ mental status and respiratory failure; atyp<✘ical symptoms usually occur early in the ™disease, including headache, muscle ac>♥hes, anorexia, fatigue, etc. . Diarrhe→ ≤a and other gastrointest✘♣φβinal symptoms are approximately 20π™"-40% . Among the atypical cases of community-acqu₽πired pneumonia, Legionella dise≥"ase is the most serious clinically,≈α and if not treated properly and in time, it ₽×♣will progressively worsen. Although there are fφ••ew extrapulmonary symptoms, it can also cause ♥₽myocarditis, pericarditis and artif★&icial valve endocardi ↑tis, as well as glomerulone ₽'¶phritis, pancreatitis and peritonitis.
【Features】
This kit uses real-time f®♠luorescent PCR technology, ta₹φkes the highly conserved r¶ ★egion of the Legionella pneumophila genome as t§™he target region, designs specific •≠primers and fluorescent probes, and the↔λ n performs PCR amplification on the t≠↕ arget sequence , while >monitoring real-time ex✔"λpansion through Taqman fluores>₩cent probe technology. Accumu™♣→lation of augmentation products enables q♠≥∞ualitative detection of Norovirus nλ©γ÷ucleic acids in samples . The reac™×tion system of this kit contains dU-UNG ©♦>₩enzyme anti-pollution s$±↑₹ystem to avoid false positive results .
【Product information】
Test specimen: throat swab
Technical principle: PCR- fluorescent ¥>&♦probe method
Packaging specificatiπ☆£ons: 24 tests/ kit, 48 tests/ kit,←ε 96 tests/ kit
Applicable instruments: Roche Cobas z 480 ↔§; Roche LightCycler 480 ; ABI 7500 ; Shan™γ<ghai Hongshi SLAN-96S ; Bioer LineGene 96¶λ€00, etc.